An internal standard for the quantification of sodium 4-phenylbutyrate by GC- or LC-MS

Sodium 4-Phenylbutyrate-d11 – 500 µg

Brand:
Cayman
CAS:
1392208-11-5
Storage:
-20
UN-No:
Non-Hazardous - /

Sodium 4-Phenylbutyrate-d11 is intended for use as an internal standard for the quantification of sodium 4-phenylbutyrate (Item No. 11323) by GC- or LC-MS. Sodium 4-phenylbutyrate is a chemical chaperone that has been shown to rescue the trafficking of misfolded proteins.{23406,23405} It also weakly blocks histone deacetylase activity (IC50 = 0.4 mM), which results in cell cycle arrest, differentiation, and/or apoptosis of various tumors.{17643,23404} Formulations containing sodium 4-phenylbutyrate have been used for the treatment of urea cycle disorders.  

 

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Description

An internal standard for the quantification of sodium 4-phenylbutyrate by GC- or LC-MS

Formal name: benzene-d5-butanoic-d6 acid, monosodium salt

Synonyms:  Benzenebutanoic acid-d11|TriButyrate-d11

Molecular weight: 197.3

CAS: 1392208-11-5

Purity: ≥99% deuterated forms (d1-d11)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|Deacetylases||Research Area|Cancer|Cell Cycle||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation

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