A nootropic phospholipid; a precursor to choline biosynthesis and an intermediate in the metabolism of phosphatidylcholine; increases acetylcholine synthesis and release in rat hippocampus; prevents scopolamine-induced amnesia in a passive avoidance test in rats; exerts neuroprotective effects in models of altered cholinergic neurotransmission and models of brain vascular injury

sn-glycero-3-Phosphocholine – 1 g

Brand:
Cayman
CAS:
28319-77-9
Storage:
-20
UN-No:
Non-Hazardous - /

sn-glycero-3-Phosphocholine (sn-glycero-3-PC) is a nootropic phospholipid, a precursor to choline biosynthesis, and an intermediate in the metabolism of phosphatidylcholine.{32447} In vivo, sn-glycero-3-PC is converted to phosphorylcholine, a metabolically active form of choline that increases acetylcholine synthesis and release in rat hippocampus. It prevents scopolamine-induced amnesia in a passive avoidance test in rats and exerts neuroprotective effects in models of altered cholinergic neurotransmission and models of brain vascular injury.{32447,45044}  

 

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Description

A nootropic phospholipid; a precursor to choline biosynthesis and an intermediate in the metabolism of phosphatidylcholine; increases acetylcholine synthesis and release in rat hippocampus; prevents scopolamine-induced amnesia in a passive avoidance test in rats; exerts neuroprotective effects in models of altered cholinergic neurotransmission and models of brain vascular injury

Formal name: 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium, inner salt

Synonyms:  sn-glycero-3-PC|Glycerophosphocholine|L-α-Glycerylphosphorylcholine|L-α-GPC

Molecular weight: 257.2

CAS: 28319-77-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Glycerophospholipids||Research Area|Lipid Biochemistry|Glycerophospholipids||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neuroprotection

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