Antigen: synthetic peptides corresponding to amino acids 186-199 and 509-523 of human SMAD4 • Host: rabbit • Cross Reactivity: (+) Human

SMAD4 Polyclonal Antibody – 100 µg

Brand:
Cayman
Storage:

Antigen: synthetic peptides corresponding to amino acids 186-199 and 509-523 of human SMAD4 • Host: rabbit • Cross Reactivity: (+) Human, new world monkey, mouse, and rat SMAD4; predicted to react with chicken, bovine, Drosophila, porcine, pufferfish, ovine, Xenopus SMAD4 • Application(s): WB • SMAD4 is a common-mediator SMAD (co-SMAD) that is part of a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor β superfamily.  

 

Available on backorder

Add to quotes
SKU: 10838- 100 µg Category:

Description

SMADs are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor β superfamily.{19294} SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD3, SMAD5, SMAD8, and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8, and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.

Synonyms:

Immunogen: synthetic peptides corresponding to amino acids 186-199 and 509-523 of human SMAD4

Formulation: 100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide

Isotype:

Applications: WB

Origin: Animal/Rabbit

Stability: 180 days

Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Signaling

Related products