Activates cardiac differentiation

Shz-1 – 50 mg

Brand:
Cayman
CAS:
326886-05-9
Storage:
-20
UN-No:
Non-Hazardous - /

Shz-1 is a Shz that activates cardiac differentiation, inducing the expression of early cardiac genes in mouse pluripotent and embryonic stem cells in vitro at low micromolar concentrations.{24724} In addition, Shz-1 drives differentiation of human peripheral blood mononuclear cells, mobilized by granule colony-stimulating factor, toward a cardiac phenotype.{24724} These Shz-1 treated cells enhance myocardial regenerative repair in cryo-injured rat heart.{24724}  

 

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Description

Activates cardiac differentiation, inducing the expression of early cardiac genes in mouse pluripotent and embryonic stem cells in vitro at low micromolar concentrations; drives differentiation of human peripheral blood mononuclear cells, mobilized by G-CSF, toward a cardiac phenotype

Formal name: benzenesulfonic acid, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide

Synonyms:  Sulfonylhydrazone-1

Molecular weight: 355.2

CAS: 326886-05-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cardiovascular System|Heart|Cardiogenesis||Research Area|Cell Biology|Stem Cell Research|Differentiation

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