A fungal metabolite; reduces Aβ aggregate-induced neurotoxicity in PC12 cells (EC50 = 112.6 μM); induces tremors in mice at 30 mg/kg

Setosusin – 2.5 mg

Brand:
Cayman
CAS:
182926-45-0
Storage:
-20
UN-No:
Non-Hazardous - /

Setosusin is a meroterpenoid fungal metabolite originally isolated from C. setosus.{41884} It reduces neurotoxicity induced by amyloid-β (Aβ) aggregates in PC12 cells (EC50 = 112.6 μM).{41885} In vivo, setosusin (30 mg/kg) induces tremors in mice.{41884}  

 

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SKU: 25484 - 2.5 mg Category:

Description

A fungal metabolite; reduces Aβ aggregate-induced neurotoxicity in PC12 cells (EC50 = 112.6 μM); induces tremors in mice at 30 mg/kg

Formal name: (1”S,2R,2’S,5”aR,7”aR,11”aR,11”bR)-1”-(acetyloxy)-1”,5”a,6”,7”,7”a,11”,11”a,11”b-octahydro-4,5,5”,5”,7”a,9”,11”b-heptamethyl-dispiro[furan-2(3H), 4′(5’H)-furan-2′(3’H),8”(5”H)-naphth[2,1-c]oxepin]-3,3”,5′(2”H)-trione

Synonyms: 

Molecular weight: 514.6

CAS: 182926-45-0

Purity: ≥99%

Formulation: A lyophilisate

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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