Description
Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly (ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene expression.{17798} Histone methyltransferases selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. SET7/9 utilizes S-adenosylmethionine to methylate histone H3 at lysine 4.{16846,17224,17917} Human SET7/9 is a 366 amino acid protein with observed migration on SDS-PAGE at 49 kDa.
Synonyms: KMT7|SET Domain-Containing Protein 7/9|SETD7/9
Immunogen: Human recombinant SET7/9 amino acids 1-366
Formulation: 400 µg of protein A-purified antibody
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Writers|Histone Methylation
