Sesquicillin A – 1 mg

Brand:
Cayman
CAS:
51103-58-3
Storage:
-20
UN-No:
- 2811 / 6.1

Sesquicillin A is a fungal metabolite that has been found in Albophoma.{49624} It inhibits the growth of A. salina brine shrimp (MIC = 6.25 µg/ml). Sesquicillin is cytotoxic to Jurkat cells (IC50 = 34 µM). It induces cell cycle arrest at the G1 phase and inhibits proliferation of MCF-7 breast cancer cells when used at a concentration of 20 µg/ml.{49625}  

 

Available on backorder

SKU: 29326 - 1 mg Category:

Description

A fungal metabolite; inhibits the growth of A. salina brine shrimp (MIC = 6.25 µg/ml); cytotoxic to Jurkat cells (IC50 = 34 µM); induces cell cycle arrest at the G1 phase and inhibits proliferation of MCF-7 breast cancer cells at 20 µg/ml


Formal name: 3-[[(1S,4aS,5R,6R,8aS)-6-(acetyloxy)decahydro-5,8a-dimethyl-2-methylene-5-(4-methyl-3-penten-1-yl)-1-naphthalenyl]methyl]-4-hydroxy-5,6-dimethyl-2H-pyran-2-one

Synonyms:  Sesquicillin

Molecular weight: 470.6

CAS: 51103-58-3

Purity: ≥70%

Formulation: A solid