A lignin with diverse biological activities; reduces lipid peroxidation in rat liver and kidneys in vivo; reduces epididymal white adipose tissue weight and serum triacylglcerol

Sesamolin – 5 mg

Brand:
Cayman
CAS:
526-07-8
Storage:
-20
UN-No:
Non-Hazardous - /

Sesamolin is a lignin found in S. indicum with diverse biological activities. It reduces lipid peroxidation in rat liver and kidneys in vivo but has no effect on lipid peroxidation activity of rat liver microsomes in vitro.{36103} In vivo, sesamolin reduces epididymal white adipose tissue weight and serum triacylglcerol, free fatty acid, phospholipid, and cholesterol concentrations in rats.{360103} Sesamolin inhibits growth of Molt-4B human lymphoid leukemia cells via induction of apoptosis in a dose-dependent manner.{360105} It also reduces hypoxia-induced lactate dehydrogynase (LDH) release and dichlorofluorescin-sensitive reactive oxygen species (ROS) production in BV-2 microglia grown under hypoxic conditions.{360106}  

 

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SKU: 11754 - 5 mg Category:

Description

A lignin with diverse biological activities; reduces lipid peroxidation in rat liver and kidneys in vivo; reduces epididymal white adipose tissue weight and serum triacylglcerol, free fatty acid, phospholipid, and cholesterol concentrations in rats; inhibits growth of Molt-4B human lymphoid leukemia cells via induction of apoptosis in a dose-dependent manner; reduces hypoxia-induced LDH release and dichlorofluorescin-sensitive ROS production in BV-2 microglia grown under hypoxic conditions,

Formal name: 5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole

Synonyms: 

Molecular weight: 370.4

CAS: 526-07-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Lignans||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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