A tetraline that inhibits monoamine transporters with selectivity for the serotonin transporter (IC50s = 70

Sertraline (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
79559-97-0
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Sertraline is a tetraline that inhibits monoamine transporters with selectivity for the serotonin transporter (IC50s = 70, 520, and 720 nM for the serotonin, dopamine, and norepinephrine transporters, respectively).{23627} It is classified as a selective serotonin reuptake inhibitor. Formulations containing sertraline are applicable to depression and related disorders.{23628,23626}  

 

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Description

A tetraline that inhibits monoamine transporters with selectivity for the serotonin transporter (IC50s = 70, 520, and 720 nM for the serotonin, dopamine, and norepinephrine transporters, respectively)

Formal name: (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine, monohydrochloride

Synonyms:  CP 51,974-1|Lustral|Seserine|Zoloft™

Molecular weight: 342.7

CAS: 79559-97-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Neuroscience|Behavioral Neuroscience|Depression

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