A synthetic peptide with neuroprotective

Semax – 10 mg

Brand:
Cayman
CAS:
80714-61-0
Storage:
-20
UN-No:
Non-Hazardous - /

Semax is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) (4-10) (Item No. 27106) that has neuroprotective, analgesic, and anxiolytic properties.{50308,50309,50310} In vivo, semax (0.3 mg/kg) reduces cortical nitric oxide (NO) production and the number of neurological disturbances, such as seizures, falling, and twisting, in a rat model of global ischemia.{50308} It decreases acetic acid-induced writhing and nociception in a hind paw compression test in mice when administered at doses ranging from 0.015 to 0.5 mg/kg.{50309} Semax also increases time spent in the open arms in the elevated plus maze, indicating anxiolytic activity, in a rat model of maternal deprivation-induced anxiety.{50310}  

 

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SKU: 27719 - 10 mg Category:

Description

A synthetic peptide with neuroprotective, analgesic, and anxiolytic properties; reduces cortical NO production and the number of neurological disturbances in a rat model of global ischemia at 0.3 mg/kg; decreases acetic acid-induced writhing and nociception in a hind paw compression test in mice from 0.015-0.5 mg/kg; increases time spent in the open arms in the elevated plus maze in a rat model of maternal deprivation-induced anxiety

Formal name: L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-L-proline

Synonyms:  ACTH4-7-PGP

Molecular weight: 813.9

CAS: 80714-61-0

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Peptides||Research Area|Neuroscience|Behavioral Neuroscience|Anxiety||Research Area|Neuroscience|Neuroprotection|Ischemia||Research Area|Neuroscience|Pain Research

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