A lignan with diverse biological activities; completely inhibits iron and cysteine-induced MDA formation in rat liver microsomes at 1 mM; reduces HIV-1 viral titers in H9 T cells (EC50 = 5.7 µM); protective against tobacco mosaic virus (TMV) infection in N. glutinosa when applied to leaves from 0.15-0.5 mM; prevents scopolamine-induced increases in hippocampal MDA and AChE levels and decreases hippocampal SOD and GPX activities

Schisanhenol – 25 mg

Brand:
Cayman
CAS:
69363-14-0
Storage:
-20
UN-No:
Non-Hazardous - /

Schisanhenol is a debenzocyclooctene lignan that has been found in Schisandraceae and has diverse biological activities.{54063,54064,54065,54066} It completely inhibits iron and cysteine-induced malondialdehyde (MDA) formation in rat liver microsomes when used at a concentration of 1 mM.{54063} Schisanhenol reduces HIV-1 viral titers in H9 T cells (EC50 = 5.7 µM).{54064} Schisanhenol is protective against tobacco mosaic virus (TMV) infection in N. glutinosa when applied to leaves at concentrations ranging from 0.15 to 0.5 mM.{54065} Schisanhenol (10, 30, or 100 mg/kg, i.p.) prevents scopolamine-induced increases in hippocampal MDA and acetylcholinesterase (AChE) levels and decreases hippocampal superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities, as well as increases time spent in the target quadrant in the Morris water maze in mice.{54066}  

 

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SKU: 30109 - 25 mg Category:

Description

A lignan with diverse biological activities; completely inhibits iron and cysteine-induced MDA formation in rat liver microsomes at 1 mM; reduces HIV-1 viral titers in H9 T cells (EC50 = 5.7 µM); protective against tobacco mosaic virus (TMV) infection in N. glutinosa when applied to leaves from 0.15-0.5 mM; prevents scopolamine-induced increases in hippocampal MDA and AChE levels and decreases hippocampal SOD and GPX activities, as well as increases time spent in the target quadrant in the Morris water maze in mice at 10, 30, or 100 mg/kg

Formal name: (6S,7R,12aR)-5,6,7,8-tetrahydro-2,3,10,11,12-pentamethoxy-6,7-dimethyl-dibenzo[a,c]cycloocten-1-ol

Synonyms:  Gomisin K3|NSC 330515|Schizanhenol

Molecular weight: 402.5

CAS: 69363-14-0

Purity: ≥98%

Formulation: A crystalline solid

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