Description
A lignan with diverse biological activities; decreases viability of U937 cells induces cell cycle arrest at the G1 phase; decreases hydrogen peroxide-induced cell death and production of ROS in C2C12 skeletal muscle cells from 5-20 μM; decreases levels of MMP-2, MMP-9, COX-2, VCAM-1, IL-1β, and TNF-α in hydrogen peroxide-stimulated C2C12 cells; decreases lipoteichoic acid-induced production of NO, PGE2, TNF-α, IL-1β, and IL-6 in mouse primary microglia; decreases serum ALT and AST activity, increases hepatic mitochondrial and total GSH levels, and reduces liver injury in a mouse model of acetaminophen-induced liver injury
Formal name: (6R,7S,13aS)-5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-cycloocta[1,2-f:3,4-f’]bis[1,3]benzodioxole
Synonyms: Schizandrin C|Wuweizisu C
Molecular weight: 384.4
CAS: 61301-33-5
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Lignans||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Research Area|Cancer|Cell Cycle|G1||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Sulfur|Glutathione||Research Area|Toxicology|Drug Metabolism|Cytochrome P450
