A selective antagonist of the dopamine D1-like receptor subtypes D1 and D5 (Kis = 0.2 and 0.3 nM

SCH 23390 (hydrochloride) – 50 mg

Brand:
Cayman
CAS:
125941-87-9
Storage:
-20
UN-No:
Non-Hazardous - /

SCH 23390 is a halobenzazepine that acts as a selective antagonist of the dopamine D1-like receptor subtypes D1 and D5 (Kis = 0.2 and 0.3 nM, respectively).{25563} In vivo studies have demonstrated that SCH 23390 can abolish pharmacologically-induced seizures.{25563} This compound is useful for studying the role of the dopamine system in normal brain function and neurological disorders.{24104,17607,11498,20951}  

 

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Description

A selective antagonist of the dopamine D1-like receptor subtypes D1 and D5 (Kis = 0.2 and 0.3 nM, respectively); useful for studying the role of the dopamine system in normal brain function and neurological disorders

Formal name: 8-chloro-2,3,4,5-tetrahydro-3-methyl-5R-phenyl-1H-3-benzazepin-7-ol, monohydrochloride

Synonyms: 

Molecular weight: 324.2

CAS: 125941-87-9

Purity: ≥99%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Seizure Disorders

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