A reversible inhibitor of both agonist and antagonist binding to diverse GPCRs; blocks the binding of radiolabeled ligands to human opioid

SCH 202676 (hydrobromide) – 25 mg

Brand:
Cayman
CAS:
265980-25-4
Storage:
-20
UN-No:
Non-Hazardous - /

SCH 202676 is a reversible inhibitor of both agonist and antagonist binding to diverse G protein-coupled receptors (GPCRs).{27649} It blocks the binding of radiolabeled ligands to human opioid, adrenergic, muscarinic, dopaminergic, adenosine, and purinergic receptors.{27649,27648,27647} It displays IC50 values of 0.1 to 1.8 µM for modulating ligand binding.{27649,27648} SCH 202676 may modulate GPCRs via thiol modification.{27646}  

 

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Description

A reversible inhibitor of both agonist and antagonist binding to diverse GPCRs; blocks the binding of radiolabeled ligands to human opioid, adrenergic, muscarinic, dopaminergic, adenosine, and purinergic receptors with IC50 values of 0.1 to 1.8 µM

Formal name: N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-methanamine, monohydrobromide

Synonyms: 

Molecular weight: 348.3

CAS: 265980-25-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology||Research Area|Neuroscience

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