A fungal metabolite; inhibits the growth of MCF-7 breast

Sartorypyrone A – 1 mg

Brand:
Cayman
CAS:
1452396-10-9
Storage:
-20
UN-No:
Non-Hazardous - /

Sartorypyrone A is a meroditerpene metabolite produced by Neosartorya fungal species.{41303} It inhibits the growth of MCF-7 breast, NCI-H460 lung, and A375-C5 melanoma cancer cell lines (GI50s = 46.3, 37.3, and 21.5 μM, respectively). Sartorypyrone A inhibits growth of Gram-positive bacteria, including multidrug-resistant S. aureus (MIC = 32 μg/ml), and reduces the mass of S. aureus and B. subtilis biofilms in vitro.{41304}  

 

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SKU: 23863 - 1 mg Category:

Description

A fungal metabolite; inhibits the growth of MCF-7 breast, NCI-H460 lung, and A375-C5 melanoma cancer cell lines (GI50s = 46.3, 37.3, and 21.5 μM, respectively); inhibits growth of Gram-positive bacteria, including multidrug-resistant S. aureus (MIC = 32 μg/ml); reduces the mass of S. aureus and B. subtilis biofilms in vitro

Formal name: rel-(+)-3-[(2E,6E)-9-[(1R,3S)-3-(acetyloxy)-2,2-dimethyl-6-methylenecyclohexyl]-3,7-dimethyl-2,6-nonadien-1-yl]-4-hydroxy-6-methyl-2H-pyran-2-one

Synonyms:  20-O-Acetyl Sartorypyrone D

Molecular weight: 456.6

CAS: 1452396-10-9

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA

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