Description
Severe acute respiratory syndrome coronavirus (SARS-CoV) nucleocapsid protein is a viral protein encoded by the N gene in SARS-CoV RNA.{53462} SARS-CoV is a member of the Betacoronavirus genus of viruses and has an approximately 79% sequence identity with SARS-CoV-2.{53459,53461} The SARS-CoV nucleocapsid protein has a greater than 90% similarity to the SARS-CoV-2 nucleocapsid protein, and SARS-CoV-2 contains 27 T cell epitopes that are identical to SARS-CoV T cell epitopes.{49555} The SARS-CoV nucleocapsid protein packages the viral RNA into a helical ribonucleoprotein complex (RNP) that is a template for viral replication.{53460} It is integral for viral self-assembly and involved with regulation of the cell cycle. SARS-CoV and SARS-CoV-2 are the causative agents of SARS and COVID-19, respectively, both of which are primarily respiratory illnesses characterized by fever, cough, and shortness of breath that can lead to life-threatening complications.{53461,55257,55258} Cayman’s SARS-CoV/SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody (Clone 001) can be used for ELISA and Western blot (WB; reducing conditions) applications.
Synonyms: SARS-CoV/SARS-CoV2 NP|SARS-CoV/SARS-CoV-2 NP|SARS-CoV/SARS-CoV2 Nucleoprotein|SARS-CoV/SARS-CoV-2 Nucleoprotein
Immunogen: Recombinant SARS-CoV nucleocapsid protein
Formulation: A liquid
Isotype: IgG
Applications: ELISA, WB (Antibody’s applications have not been validated with corresponding viruses. Optimal concentrations/dilutions should be determined by the end user.)
Origin:
Stability: 365 days
Application|ELISA||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Immunology & Inflammation|Pulmonary Diseases|COVID-19||Research Area|Immunology & Inflammation|Pulmonary Diseases|MERS||Research Area|Infectious Disease|Viral Diseases|Coronaviruses
