Description
A homoisoflavonoid with diverse biological activities; inhibits FGFR1, KDR, c-Met, and c-Kit kinase activity (10 μM); inhibits viral NA (IC50s = 0.7, 1.1, and 1 μM for H1N1, H3N2, and H9N2 influenza viral NAs, respectively); has antibacterial and antifungal activities; reduces NO, IL-6, and PGE2 production in RAW264.7 cells; attenuates airway inflammation and mucus hypersecretion in a mouse model of ovalbumin-induced asthma
Formal name: (3E)-3-[(3,4-dihydroxyphenyl)methylene]-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
Synonyms:
Molecular weight: 284.3
CAS: 104778-14-5
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Antivirals|Neuraminidase Inhibitors||Product Type|Biochemicals|Kinase Inhibitors|FGFR Family||Product Type|Biochemicals|Kinase Inhibitors|Other Receptor Tyrosine Kinases||Product Type|Biochemicals|Kinase Inhibitors|PDGFR Family||Product Type|Biochemicals|Kinase Inhibitors|VEGFR Family||Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|Growth Factor Receptors||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Fungal Diseases|Candidiasis||Research Area|Infectious Disease|Viral Diseases|Influenza
