A semi-synthetic tetracycline antibiotic; more active than tetracycline against 339 strains of anaerobic bacteria (MIC90s = 1 and 32 μg/ml

Sancycline – 250 mg

Brand:
Cayman
CAS:
808-26-4
Storage:
-20
UN-No:
Non-Hazardous - /

Sancycline is a semi-synthetic tetracycline antibiotic that is more active than tetracycline (Item No. 14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 μg/ml, respectively).{41112,41113} Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from 0.06 to 1 μg/ml.{41114} In vivo, sancycline is active against S. aureus in mice with ED50 values of 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively.  

 

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SKU: 23100 - 250 mg Category:

Description

A semi-synthetic tetracycline antibiotic; more active than tetracycline against 339 strains of anaerobic bacteria (MIC90s = 1 and 32 μg/ml, respectively); active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains (MICs = 0.06-1 μg/ml); active against S. aureus in mice (ED50s = 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively)

Formal name: 4-(dimethylamino)-1,4S,4aS,5,5aR,6,11,12aS-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide

Synonyms:  6-Demethyl-6-deoxytetracycline|GS 2147

Molecular weight: 414.4

CAS: 808-26-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Tetracyclines||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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