An intermediate in the de novo purine nucleotide synthesis pathway; stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in conditions of limited glucose availability

SAICAR – 500 µg

Brand:
Cayman
CAS:
3031-95-6
Storage:
-20
UN-No:
Non-Hazardous - /

SAICAR is an intermediate in the de novo purine nucleotide synthesis pathway. It is reported to stimulate pyruvate kinase isoform M2 and to promote cancer cell survival in conditions of limited glucose availability.{21962}  

 

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Description

An intermediate in the de novo purine nucleotide synthesis pathway; stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in conditions of limited glucose availability

Formal name: N-[[5-amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazol-4-yl]carbonyl]-L-aspartic acid

Synonyms:  Succino-AICAR|Succinyl-5-aminoimidazole-4-carboxamide-1-ribose-5′-phosphate

Molecular weight: 454.3

CAS: 3031-95-6

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Cancer|Metabolism

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