An internal standard for the quantification of SAHA by GC- or LC-MS

SAHA-d5 – 1 mg

Brand:
Cayman
CAS:
1132749-48-4
Storage:
-20
UN-No:
Non-Hazardous - /

SAHA-d5 contains five deuterium atoms at the 2, 3, 4, 5, and 6 positions. It is intended for use as an internal standard for the quantification of SAHA (suberoylanilide hydroxamic acid; Item No. 10009929) by GC- or LC-MS. SAHA is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I, II, and IV HDACs at 50-200 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.{14739}  

 

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Description

An internal standard for the quantification of SAHA by GC- or LC-MS,

Formal name: N1-hydroxy-N8-(phenyl-2,3,4,5,6-d5)-octanediamide

Synonyms:  Suberoylanilide Hydroxamic Acid-d5|Vorinostat-d5

Molecular weight: 269.4

CAS: 1132749-48-4

Purity: ≥99% deuterated forms (d1-d5)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|Deacetylases||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation

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