Description
EDG-6 is a member of the endothelial differentiation gene (EDG) G protein-coupled receptor family and is a receptor for sphingosine 1-phosphate (S1P). Binding of S1P to EDG-6 activates Erk, leading to the activation of the transcription factor Elk1 and thus the mitogen-activated protein kinase (MAPK) signal transduction pathway. The protein is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Human EDG-6 gene is intronless and is mapped to chromosome 19p13.3 at the D19S120 marker.
Synonyms: EDG-6|S1PR4|Sphingosine-1-phosphate Receptor 4
Immunogen: synthetic peptide from human S1P4 within the region of amino acids 1-50
Formulation: 100 µg of peptide affinity-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide.
Isotype:
Applications: WB, IF, and ICC
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunocytochemistry||Application|Immunofluorescence||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity
