A non-selective COX inhibitor and NSAID (IC50s = 0.1 and 2.7 µM for COX-1 and COX-2

(S)-Ketorolac – 5 mg

Brand:
Cayman
CAS:
66635-92-5
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

(S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 µM for COX-1 and COX-2, respectively).{20315} (S)-Ketorolac is approximately twice as potent as the racemic mixture (Item No. 9001148) and 60 times more potent than (R)-ketorolac in a rat pain assay.{34230} (S)-Ketorolac is cleared from rat kidney and liver more quickly than (R)-ketorolac.{34229} Formulations containing ketorolac have been used to manage postoperative pain as well as an ophthalmic solution to treat ocular pain and inflammation.{10631}  

 

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SKU: 11348 - 5 mg Category:

Description

A non-selective COX inhibitor and NSAID (IC50s = 0.1 and 2.7 µM for COX-1 and COX-2, respectively); (S)-ketorolac is approximately twice as potent as the racemic mixture and 60 times more potent than (R)-ketorolac

Formal name: (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

Synonyms:  (-)-Ketorolac

Molecular weight: 255.3

CAS: 66635-92-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology||Research Area|Neuroscience|Pain Research

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