EPIT is a selective

S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
163490-78-6
Storage:
-20
UN-No:
Non-Hazardous - /

EPIT is a selective, competitive inhibitor of nNOS having a Ki of 0.32 µM for the purified human enzyme. EPIT exhibits 115-fold and 29-fold selectivity for nNOS compared to iNOS and eNOS, respectively. It exhibits reduced inhibitory potency in whole-cell assays, possibly due to reduced intracellular uptake.{5065}  

 

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SKU: 81280 - 10 mg Category:

Description

EPIT is a selective, competitive inhibitor of nNOS having a Ki of 0.32 µM for the purified human enzyme. EPIT exhibits 115-fold and 29-fold selectivity for nNOS compared to iNOS and eNOS, respectively. It exhibits reduced inhibitory potency in whole-cell assays, possibly due to reduced intracellular uptake.{5065}

Formal name: ethyl[4-(trifluoromethyl)phenyl] carbamimidothioate, hydrochloride

Synonyms:  EPIT

Molecular weight: 284.7

CAS: 163490-78-6

Purity: ≥98%

Formulation: A crystalline solid

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