A CB1 receptor ligand with less potency than R-1 methanandamide; inhibits electrically evoked contractions in isolated murine vas deferens (IC50 = 230 nM); binding affinity for CB1 receptors is less than that of AEA (Ki = 175 nM for the displacement of radiolabeled CP 55

S-1 Methanandamide – 25 mg

Brand:
Cayman
CAS:
157182-50-8
Storage:
-20
UN-No:
De Minimis - 1170 / 3

S-1 methanandamide is a CB1 receptor ligand but is less potent than the C-1 (R) methyl isomer. It inhibits electrically evoked contractions in isolated mouse vasa deferentia with an IC50 value of 230 nM. The binding affinity of S-1 methanandamide for CB1 receptors is less than that of AEA, with a Ki of 175 nM for the displacement of radiolabeled CP 55,940.{1092}  

 

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SKU: 90072 - 25 mg Category:

Description

A CB1 receptor ligand with less potency than R-1 methanandamide; inhibits electrically evoked contractions in isolated murine vas deferens (IC50 = 230 nM); binding affinity for CB1 receptors is less than that of AEA (Ki = 175 nM for the displacement of radiolabeled CP 55,940)

Formal name: N-(2-hydroxy-1S-methylethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide

Synonyms:  (S)-(−)-Arachidonyl-1′-Hydroxy-2′-Propylamide

Molecular weight: 361.6

CAS: 157182-50-8

Purity: ≥98%

Formulation: A solution in ethanol

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