A natural non-caloric sweetener; inhibits glucose transport by Glut 1 and fructose transport by Glut5 (IC50s = 4.6 and 6.7 mM

Rubusoside – 10 mg

Brand:
Cayman
CAS:
64849-39-4
Storage:
-20
UN-No:
- /

Rubusoside is a natural non-caloric sweetener and glycoside form of steviol (Item No. 10011344) that has been found in S. rebaudiana leaves and has diverse biological activities.{46536,46537} It inhibits glucose transport by glucose transporter 1 (Glut1) and fructose transport by Glut5 (IC50s = 4.6 and 6.7 mM, respectively, for the recombinant human transporters).{46538} Rubusoside prevents lipotoxicity induced by palmitic acid (Item No. 10006627) in INS-1 mouse insulinoma cells when used at concentrations ranging from 50 to 200 µM.{46539} It has been used to enhance the solubility of the anticancer agent etoposide (Item No. 12092).{46540}  

 

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SKU: 29040 - 10 mg Category:

Description

A natural non-caloric sweetener; inhibits glucose transport by Glut 1 and fructose transport by Glut5 (IC50s = 4.6 and 6.7 mM, respectively, for the recombinant human transporters); prevents palmitic acid-induced lipotoxicity in INS-1 mouse insulinoma cells at 50-200 µM; has been used to enhance the solubility of etoposide

Formal name: (4α)-13-(β-D-glucopyranosyloxy)-kaur-16-en-18-oic acid, β-D-glucopyranosyl ester

Synonyms: 

Molecular weight: 642.7

CAS: 64849-39-4

Purity: ≥98%

Formulation: A crystalline solid

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