A potent HMG-CoA reductase inhibitor (IC50 = 5 nM); a fully-synthetic inhibitor that is designed to maximize the points of contact with

Rosuvastatin – 100 mg

Brand:
Cayman
CAS:
287714-41-4
Storage:
-20
UN-No:
Non-Hazardous - /

Rosuvastatin is a potent HMG-CoA reductase inhibitor (IC50 = 5 nM).{15309,15082} It is a fully-synthetic inhibitor that is designed to maximize the points of contact with, and inhibition of, HMG-CoA reductase.{15309} Formulations containing rosuvastatin reduce low-density lipoprotein (LDL) and C-reactive protein and increase high-density lipoprotein (HDL) in humans.{16178,30471}  

 

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SKU: 12029 - 100 mg Category:

Description

A potent HMG-CoA reductase inhibitor (IC50 = 5 nM); a fully-synthetic inhibitor that is designed to maximize the points of contact with, and inhibition of, HMG-CoA reductase

Formal name: 7-[4-(4-fluorophenyl)-6E-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3R,5S-dihydroxy-6-heptenoic acid

Synonyms:  ZD 4522

Molecular weight: 481.5

CAS: 287714-41-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cardiovascular System|Blood|Acute Phase Reactants||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins

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