(–)-Ropivacaine (hydrochloride hydrate) – 250 mg

Brand:
Cayman
CAS:
132112-35-7
Storage:
-20
UN-No:
Non-Hazardous - /

(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers.{33665} In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve.{42580} (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine (Item No. 16618).{42581} Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.  

 

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SKU: 21422 - Category:

Description

A potent and reversible sodium channel blocker; induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve; depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine ,


Formal name: (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide, monohydrochloride, monohydrate

Synonyms:  (S)-Ropivacaine|LEA 103

Molecular weight: 328.9

CAS: 132112-35-7

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Ion Channel Modulation|Blockers||Research Area|Neuroscience