An internal standard for the quantification of (–)-ropivacaine by GC- or LC-MS

(–)-Ropivacaine-d7 (hydrochloride) – 1 mg

Brand:
Cayman
CAS:
1217667-10-1
Storage:
-20
UN-No:
Non-Hazardous - /

(–)-Ropivacaine-d7 is intended for use as an internal standard for the quantification of (–)-ropivacaine (Item No. 21422) by GC- or LC-MS. (–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers.{33665} In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve.{42580} (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine (Item No. 16618).{42581} Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.  

 

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Description

An internal standard for the quantification of (–)-ropivacaine by GC- or LC-MS,

Formal name: (S)-N-(2,6-dimethylphenyl)-1-(propyl-d7)piperidine-2-carboxamide, monohydrochloride

Synonyms:  (S)-Ropivacaine-d7

Molecular weight: 317.9

CAS: 1217667-10-1

Purity: ≥99% deuterated forms (d1-d7)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Research Area|Neuroscience

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