An internal standard for the quantification of rivaroxaban by GC- or LC-MS

Rivaroxaban-d4 – 1 mg

Brand:
Cayman
CAS:
1132681-38-9
Storage:
-20
UN-No:
Non-Hazardous - /

Rivaroxaban-d4 is intended for use as an internal standard for the quantification of rivaroxaban (Item No. 16043) by GC- or LC-MS. Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade.{25094} It demonstrates >10,000-fold greater selectivity for Factor Xa compared to other related serine proteases. In various animal arterial and venous thrombosis models, rivaroxaban is reported to inhibit thrombin formation without prolonging bleeding time. Formulations containing rivaroxaban have been used as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms.{26130,26131}  

 

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Description

An internal standard for the quantification of rivaroxaban by GC- or LC-MS

Formal name: 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl-2,3,5,6-d4]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide

Synonyms: 

Molecular weight: 439.9

CAS: 1132681-38-9

Purity: ≥99% deuterated forms (d1-d4)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|Blood Coagulation Factors||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis||Research Area|Cardiovascular System|Cardiovascular Diseases|Stroke

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