An orally active

Rivaroxaban – 5 mg

Brand:
Cayman
CAS:
366789-02-8
Storage:
-20
UN-No:
Non-Hazardous - /

Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade.{25094} It demonstrates >10,000-fold greater selectivity for Factor Xa compared to other related serine proteases.{25094} In various animal arterial and venous thrombosis models, rivaroxaban is reported to inhibit thrombin formation without prolonging bleeding time and has been approved for clinical use as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms.{26130,26131}  

 

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Description

An orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM) that inhibits thrombin formation without prolonging bleeding time; approved for clinical use as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms

Formal name: 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide

Synonyms:  BAY 59-7939

Molecular weight: 435.9

CAS: 366789-02-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Blood Coagulation Factors||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis

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