An inhibitor of FMN riboswitch-mediated expression of ribB

Ribocil – 1 mg

Brand:
Cayman
CAS:
1381289-58-2
Storage:
-20
UN-No:
Non-Hazardous - /

Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN; Item No. 18167) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB, a gene responsible for the synthesis and transport of riboflavin.{29669} Ribocil depletes cellular levels of riboflavin with an IC50 value of 0.3 µM and inhibits E. coli growth with an MIC value of 2 µg/ml.{29669}  

 

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Description

An inhibitor of FMN riboswitch-mediated expression of ribB, a gene responsible for the synthesis and transport of riboflavin; depletes cellular levels of riboflavin (IC50 = 0.3 µM) and inhibits E. coli growth (MIC = 2 µg/ml)

Formal name: 2-[1-[[2-(methylamino)-5-pyrimidinyl]methyl]-3-piperidinyl]-6-(2-thienyl)-4(3H)-pyrimidinone

Synonyms: 

Molecular weight: 382.5

CAS: 1381289-58-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Research Area|Immunology & Inflammation

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