A natural analog of resveratrol with antioxidant and anti-cancer activity; a mechanism-based

Rhapontigenin – 25 mg

Brand:
Cayman
CAS:
500-65-2
Storage:
-20
UN-No:
Non-Hazardous - /

Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.{17506} At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).{17507,17129}  

 

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Description

A natural analog of resveratrol with antioxidant and anti-cancer activity; a mechanism-based, selective inactivator of CYP450 1A1 (IC50 = 400 nM); inhibits the proliferation of cancer cell lines (IC50 = 48 μM)

Formal name: 5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-1,3-benzenediol

Synonyms: 

Molecular weight: 258.3

CAS: 500-65-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Research Area|Cancer||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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