A synthetic compound made up of the arginine-glycine-aspartate motif used to inhibit integrin-ligand interactions in studies related to cell adhesion

RGD Peptide – 25 mg

Brand:
Cayman
CAS:
114681-65-1
Storage:
-20
UN-No:
Non-Hazardous - /

RGD peptide is a synthetic compound made up of the arginine-glycine-aspartate motif that has been extensively used to inhibit integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.{5588} RGD peptide has also been shown to directly induce apoptosis, independent of integrin-mediated cell clustering or signals, by initiating conformational changes that enhance pro-caspase-3 activation and autoprocessing.{7006,8479}  

 

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Description

A synthetic compound made up of the arginine-glycine-aspartate motif used to inhibit integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation; also can directly induce apoptosis by activating pro-caspase-3

Formal name: glycyl-L-arginylglycyl-L-α-aspartyl-L-asparaginyl-L-proline

Synonyms:  GRGDNP|H-Gly-Arg-Gly-Asp-Asn-Pro-OH

Molecular weight: 614.6

CAS: 114681-65-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Peptides||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|ECM & Adhesion Molecules

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