A bacterial metabolite; inhibits EGF-induced mitogenic activity in Balb/MK cells; has pH-dependent antifungal activity against C. albicans (MICs = 2.0 and >500 μg/ml at pH 3.0 and 7.4

Reveromycin D – 1 mg

Brand:
Cayman
CAS:
144860-70-8
Storage:
-20
UN-No:
Non-Hazardous - /

Reveromycin D is a bacterial metabolite originally isolated from Streptomyces.{47366} It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μg/ml at pH 3 and 7.4, respectively).{28254} Reveromycin D also inhibits proliferation of KB and K562 cells (IC50s = 1.6 and 1.3 μg/ml, respectively).  

 

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SKU: 28101 - 1 mg Category:

Description

A bacterial metabolite; inhibits EGF-induced mitogenic activity in Balb/MK cells; has pH-dependent antifungal activity against C. albicans (MICs = 2.0 and >500 μg/ml at pH 3.0 and 7.4, respectively); inhibits proliferation of KB and K562 cells (IC50s = 1.6 and 1.3 μg/ml, respectively)

Formal name: butanedioic acid, 1-[(2S,3R,6S,8R,9S)-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-3-pentyl-1,7-dioxaspiro[5.5]undec-3-yl] ester

Synonyms: 

Molecular weight: 674.8

CAS: 144860-70-8

Purity: ≥95%

Formulation: A lyophilisate

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