A pleuromutilin antibiotic that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation

Retapamulin – 5 mg

Brand:
Cayman
CAS:
224452-66-8
Storage:
-20
UN-No:
Non-Hazardous - /

Retapamulin is a pleuromutilin antibiotic that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation.{22680} It has activity against staphylococcal, streptococcal, and anaerobic Gram-positive bacteria.{22680}  

 

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Description

A pleuromutilin antibiotic that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation

Formal name: 2-[[(3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]thio]-acetic acid, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester

Synonyms:  SB-275833

Molecular weight: 517.8

CAS: 224452-66-8

Purity: ≥99%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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