Increases the activity of angiotensin-converting enzyme 2 (ACE2) in vitro (EC50 = 19.5 μM)

Resorcinolnaphthalein – 5 mg

Brand:
Cayman
CAS:
41307-63-5
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM).{16242} Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.{16242}  

 

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Description

Increases the activity of angiotensin-converting enzyme 2 (ACE2) in vitro (EC50 = 19.5 μM)

Formal name: 3′,6′-dihydroxy-spiro[1H,3H-naphtho[1,8-cd]pyran-1,9′-[9H]xanthen-3-one

Synonyms:  NSC 354317

Molecular weight: 382.4

CAS: 41307-63-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Angiotensin-converting Enzyme||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Heart||Research Area|Cardiovascular System|Kidney & Renal Disease

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