An internal standard for the quantification of repaglinide by GC- or LC-MS

Repaglinide-d5 – 500 µg

Brand:
Cayman
CAS:
1217709-85-7
Storage:
-20
UN-No:
Non-Hazardous - /

Repaglinide-d5 is intended for use as an internal standard for the quantification of repaglinide (Item No. 19387) by GC- or LC-MS. Repaglinide is a metaglitinide antidiabetic agent that blocks ATP-dependent potassium (Kir6) channels in pancreatic β-cells (Kd = 0.42 nM for the sulphonylurea receptor SUR1 when co-expressed with Kir6.2).{32299} In vivo, repaglinide lowers blood glucose in fasted rats and dogs (ED50s = 10 and 28.3 μg/kg, respectively).{32300} Formulations containing repaglinide have been used to control blood sugar levels in patients with type 2 diabetes.  

 

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SKU: 26104 - 500 µg Category:

Description

An internal standard for the quantification of repaglinide by GC- or LC-MS,

Formal name: 2-(ethoxy-1,1,2,2,2-d5)-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-benzoic acid

Synonyms: 

Molecular weight: 457.6

CAS: 1217709-85-7

Purity: ≥99% deuterated forms (d1-d5)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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