Recombinant Human FGF2 Protein – 100ug/vial

Brand:
Boster Bio
Storage:
-20ºC

Fibroblast Growth Factor basic (FGF-basic/FGF-2) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FGF-1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor. Other homologous FGF belonging to the same family are int-2 (FGF-3), FGF-5, FGF-6, K-FGF and KGF ( keratinocyte growth factor = FGF-7). All factors are products of different genes, some of which are Oncogene products ( FGF-3, FGF-4, FGF-5 ).

Available on backorder

SKU: R00121 Category:

Description

Amino acid sequence: PALPE DGGSG AFPPG HFKDP KRLYC KNGGF FLRIH PDGRV DGVRE KSDPH IKLQL QAEER GVVSI KGVCA NRYLA MKEDG RLLAS KCVTD ECFFF ERLES NNYNT YRSRK YTSWY VALKR TGQYK LGSKT GPGQK AILFL PMSAK S

Source: E. Coli-derived P143-S288

Species: human

Purity: >95%, by SDS-PAGE quantitative densitometry by Coomassie® Blue Staining.

Molecular Weight: 16.5KD

Formulation: Lyophilized after extensive dialysis against PBS.

Reconstitution: Reconstitute in ddH2O at 100 μg/mL.

Endotoxin: Less than 1 EU/μg of rHubFGF as determined by LAL method.

Storage: Lyophilized recombinant mouse Fibroblast Growth Factor basic (FGF-basic/FGF-2) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF2 remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.