A potent dopamine D4 receptor antagonist (Ki = 0.3 nM) that is selective over D2L

RBI 257 (maleate) – 1 mg

Brand:
Cayman
CAS:
911378-38-6
Storage:
-20
UN-No:
Non-Hazardous - /

RBI 257 is a potent dopamine D4 receptor antagonist (Ki = 0.3 nM) that is selective over D2L, D3, D2-like, and D1 receptors by 1,721-, 439-, 1,336-, and 8,576-fold, respectively.{28464}  

 

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Description

A potent dopamine D4 receptor antagonist (Ki = 0.3 nM) that is selective over D2L, D3, D2-like, and D1 receptors by 1,721-, 439-, 1,336-, and 8,576-fold, respectively.{28464}

Formal name: N-[1-[(4-iodophenyl)methyl]-4-piperidinyl]-N-methyl-3-(1-methylethoxy)-2-pyridinamine (2Z)-2-butenedioate

Synonyms: 

Molecular weight: 581.4

CAS: 911378-38-6

Purity: ≥95%

Formulation: A crystalline solid

Application||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience

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