An internal standard for the quantification of ranitidine by GC- or LC-MS

Ranitidine-d6 (hydrochloride) – 1 mg

Brand:
Cayman
CAS:
1185238-09-8
Storage:
-20
UN-No:
Non-Hazardous - /

Ranitidine-d6 is intended for use as an internal standard for the quantification of ranitidine (Item No. 16939) by GC- or LC-MS. Ranitidine is a histamine H2 receptor antagonist.{27474} It reverses histamine-induced relaxation of isolated rat uterine horn (pA2 = 6.9) as well as histamine-induced increases in contraction frequency in isolated guinea pig right atrium (pA2 = 7.2). Ranitidine (0.03-3 mg/kg, i.v.) inhibits histamine-and pentagastrin-induced gastric acid secretion in a dose-dependent manner in anesthetized rats. Formulations containing ranitidine have been used in the treatment and prevention of heartburn and gastroesophageal reflux disease (GERD).  

 

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Description

An internal standard for the quantification of ranitidine by GC- or LC-MS,

Formal name: (E)-N-(2-(((5-((bis(methyl-d3)amino)methyl)furan-2-yl)methyl)thio)ethyl)-N’-methyl-2-nitroethene-1,1-diamine, monohydrochloride

Synonyms: 

Molecular weight: 356.9

CAS: 1185238-09-8

Purity: ≥99% deuterated forms (d1-d6)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area

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