An internal standard for the quantification of ramipril by GC- or LC-MS

Ramipril-d5 – 1 mg

Brand:
Cayman
CAS:
1132661-86-9
Storage:
-20
UN-No:
Non-Hazardous - /

Ramipril-d5 is intended for use as an internal standard for the quantification of ramipril (Item No. 15558) by GC- or LC-MS. Ramipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor ramiprilat (Item No. 15557).{23056} Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats.{36825} It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis.{36826} Ramipril also decreases paw swelling and serum levels of TNF-α and prostaglandin E2 (PGE2) as well as cardiac collagen deposition and fibrosis in a rat model of adjuvant-induced arthritis.{36827}  

 

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SKU: 25425 - 1 mg Category:

Description

An internal standard for the quantification of ramipril by GC- or LC-MS

Formal name: (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-(phenyl-2,3,4,5,6-d5)propyl]amino]-1-oxopropyl]octahydro-cyclopenta[b]pyrrole-2-carboxylic acid

Synonyms:  Altace-d5

Molecular weight: 421.5

CAS: 1132661-86-9

Purity: ≥99% deuterated forms (d1-d5)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|Angiotensin-converting Enzyme||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins

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