An anthelmintic; completely eradicates E. caproni infection in mice at 50 mg/kg; active against H. contortus in sheep at 10 mg/kg and eliminates mature F. hepatica flukes in cattle at 7.5 mg/kg; cytotoxic to A375 and A431 skin cancer cells in vitro (IC50s = 10.9 and 1.31 µM

Rafoxanide – 500 mg

Brand:
Cayman
CAS:
22662-39-1
Storage:
-20
UN-No:
Non-Hazardous - /

Rafoxanide is an anthelmintic.{52259,52260,52261} In vivo, rafoxanide (50 mg/kg) completely eradicates E. caproni infection in mice.{52259} It is active against H. contortus in sheep when administered at a dose of 10 mg/kg and eliminates mature F. hepatica flukes in cattle when administered at a dose of 7.5 mg/kg.{52260,52261} It is also cytotoxic to A375 and A431 skin cancer cells in vitro (IC50s = 10.9 and 1.31 µM, respectively) and reduces tumor growth in an A375 mouse xenograft model when administered at a dose of 40 mg/kg.{52261} Formulations containing rafoxanide have been used in the treatment of parasitic infections in sheep and cattle.  

 

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SKU: 29616 - 500 mg Category:

Description

An anthelmintic; completely eradicates E. caproni infection in mice at 50 mg/kg; active against H. contortus in sheep at 10 mg/kg and eliminates mature F. hepatica flukes in cattle at 7.5 mg/kg; cytotoxic to A375 and A431 skin cancer cells in vitro (IC50s = 10.9 and 1.31 µM, respectively); reduces tumor growth in an A375 mouse xenograft model at 40 mg/kg

Formal name: N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo-benzamide

Synonyms:  NSC 355278

Molecular weight: 626

CAS: 22662-39-1

Purity: ≥98%

Formulation: A crystalline solid

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