A quinomycin antibiotic; active against a variety of bacteria

Quinaldopeptin – 2.5 mg

Brand:
Cayman
CAS:
130743-07-6
Storage:
-20
UN-No:
Non-Hazardous - /

Quinaldopeptin is a quinomycin antibiotic.{45259} It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1, and 6.3 µg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 µg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).{45260}  

 

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SKU: 28167 - 2.5 mg Category:

Description

A quinomycin antibiotic; active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1, and 6.3 µg/ml, respectively); cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 µg/ml, respectively); increases survival in a P388 leukemia mouse model; binds to and intercalates into DNA (Kd = 32 nM)

Formal name:

Synonyms: 

Molecular weight: 1,243.40

CAS: 130743-07-6

Purity: ≥95%

Formulation: A powder

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