A triterpene saponin with diverse biological activities; cytotoxic to SNU-1 and KATO III gastric cancer cells (IC50s = 13.6 and 67 µM

Quillaic Acid – 10 mg

Brand:
Cayman
CAS:
631-01-6
Storage:
-20
UN-No:
Non-Hazardous - /

Quillaic acid is a triterpene saponin that has been found in Q. saponaria bark and has diverse biological activities.{54478,54479,54480} It is cytotoxic to SNU-1 and KATO III gastric cancer cells (IC50s = 13.6 and 67 µM, respectively).{54478} Quillaic acid induces hot plate analgesia in mice (ED50 = 20.7 mg/kg).{54479} It reduces ear edema induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) or phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice when administered topically at doses of 0.7 and 1.6 mg/ear, respectively.{54480}  

 

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SKU: 31512 - 10 mg Category:

Description

A triterpene saponin with diverse biological activities; cytotoxic to SNU-1 and KATO III gastric cancer cells (IC50s = 13.6 and 67 µM, respectively); induces hot plate analgesia in mice (ED50 = 20.7 mg/kg); reduces arachidonic acid- or TPA-induced ear edema in mice when administered at 0.7 and 1.6 mg/ear, respectively

Formal name: (3β,4α,16α)-3,16-dihydroxy-23-oxo-olean-12-en-28-oic acid

Synonyms:  Quillaja Sapogenin

Molecular weight: 486.7

CAS: 631-01-6

Purity: ≥98%

Formulation: A crystalline solid

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