A phenol with antioxidant activity; scavenges DPPH radicals in a cell-free assay (IC50 = 48.6 µM); inhibits H. pylori-induced oxidative burst of isolated rat PMNs (IC50 = 75.3 µM); prevents blue light-induced retinal degeneration in a mouse model of macular degeneration at 25

Quercetin 3-O-α-L-arabinopyranoside – 5 mg

Brand:
Cayman
CAS:
22255-13-6
Storage:
-20
UN-No:
Non-Hazardous - /

Quercetin 3-O-α-L-arabinopyranoside is a phenol that has been found in Byrsonima crassa and has antioxidant activity.{61102,61103} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 48.6 µM).{61102} Quercetin 3-O-α-L-arabinopyranoside inhibits H. pylori-induced oxidative burst of isolated rat polymorphonuclear (PMN) neutrophils (IC50 = 75.3 µM).{61103} It reduces N-retinylidene-N-retinylethanolamine- and blue light-induced death of ARPE-19 retinal epithelial cells in a concentration-dependent manner.{61104} In vivo, quercetin 3-O-α-L-arabinopyranoside (25, 50, and 200 mg/kg) prevents blue light-induced retinal degeneration in a mouse model of macular degeneration.  

 

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Description

A phenol with antioxidant activity; scavenges DPPH radicals in a cell-free assay (IC50 = 48.6 µM); inhibits H. pylori-induced oxidative burst of isolated rat PMNs (IC50 = 75.3 µM); prevents blue light-induced retinal degeneration in a mouse model of macular degeneration at 25, 50, and 75 mg/kg

Formal name: 3-(α-L-arabinopyranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one

Synonyms:  Guaijaverin

Molecular weight: 434.4

CAS: 22255-13-6

Purity: ≥98%

Formulation: A crystalline solid

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