Description
A flavonol that selectively inhibits Pim-1 (IC50 = 0.34 µM) compared to Pim-2, PKA, RSK2, and JNK (IC50s = 3.45, 21.2, 2.82, and 4.6 µM, respectively); inhibits Pim-1 activity in intact RWPE2 prostate cancer cells (ED50 = 5.5 µM) significantly inhibiting their growth
Formal name: 2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-1-benzopyran-4-one
Synonyms: 6-hydroxy Quercetin|NSC 115916
Molecular weight: 318.2
CAS: 90-18-6
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|PIMs||Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|PIM Signaling||Research Area|Cell Biology|Cell Signaling