A fungal metabolite with antioxidant activity; scavenges DPPH free radicals in a cell-free assay (IC50 = 132.9 μM); suppresses TNF-α-induced expression of VCAM-1 in HUVECs at 10 μM

Pyranonigrin A – 1 mg

Brand:
Cayman
CAS:
773855-65-5
Storage:
-20
UN-No:
- /

Pyranonigrin A is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity.{49097} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) free radicals in a cell-free assay (IC50 = 132.9 μM). Pyranonigrin A (10 μM) suppresses TNF-α-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs).  

 

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SKU: 27535 - 1 mg Category:

Description

A fungal metabolite with antioxidant activity; scavenges DPPH free radicals in a cell-free assay (IC50 = 132.9 μM); suppresses TNF-α-induced expression of VCAM-1 in HUVECs at 10 μM

Formal name: (7R)-6,7-dihydro-3,7-dihydroxy-2-(1E)-1-propen-1-yl-pyrano[2,3-c]pyrrole-4,5-dione

Synonyms:  7-hydroxy Pyranonigrin S

Molecular weight: 223.2

CAS: 773855-65-5

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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