An active metabolite of PX-866; inhibits PI3Kα

PX-866-17OH – 5 mg

Brand:
Cayman
CAS:
1012327-63-7
Storage:
-20
UN-No:
Non-Hazardous - /

PX-866-17OH is an active metabolite of PX-866 (Item No. 13645).{47566} It inhibits PI3Kα, PI3Kβ, PI3Kɣ, and PI3Kδ (IC50s = 14, 57, 131, and 148 nM, respectively).  

 

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SKU: 21204 - Category:

Description

An active metabolite of PX-866; inhibits PI3Kα, PI3Kβ, PI3Kɣ, and PI3Kδ (IC50s = 14, 57, 131, and 148 nM, respectively)

Formal name: (1E,4S,4aR,5R,6aS,7S,9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino)methylene]-4a,5,6,6a,7,8,9,9a-octahydro-7,11-dihydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta[5,6]naphtho[1,2-c]pyran-2,10(1H,4H)-dione

Synonyms: 

Molecular weight: 527.6

CAS: 1012327-63-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|PI3K||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling

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