An oleanane-type saponin with anticancer activity; cytotoxic to A549

Pulsatilla Saponin D – 1 mg

Brand:
Cayman
CAS:
68027-15-6
Storage:
-20
UN-No:
Non-Hazardous - /

Pulsatilla saponin D is an oleanane-type saponin that has been found in P. koreana and has anticancer activity.{52250} It is cytotoxic to A549, SKOV3, SK-MEL-2, and HCT15 cells (EC50s = 11.25, 13.17, 3.04, and 11.86 μM, respectively). Pulsatilla saponin D (6 mg/kg per day) reduces tumor volume in a murine Lewis lung carcinoma model.  

 

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SKU: 29455 - 1 mg Category:

Description

An oleanane-type saponin with anticancer activity; cytotoxic to A549, SKOV3, SK-MEL-2, and HCT15 cells (EC50s = 11.25, 13.17, 3.04, and 11.86 μM, respectively); reduces tumor volume in a murine Lewis lung carcinoma model at 6 mg/kg per day

Formal name: (3β,4α)-3-[[O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl]oxy]-23-hydroxy-olean-12-en-28-oic acid

Synonyms:  Hederacolchiside A|Hederagenin 3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranoside|Pulchinenoside B3

Molecular weight: 913.1

CAS: 68027-15-6

Purity: ≥98%

Formulation: A solid

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