Description
An uncharged, 1,4-di-substituted, phenyl-linked bis-TFMS phosphate mimetic that acts as a reversible, competitive, and active-site directed inhibitor of SHP-2, PTP1B, PTP-ε, PTP-Meg-2, PTP-σ, PTP-β, and PTP-µ (IC50s = 1.8, 2.5, 8.4, 13, 20, 6.4, and 6.7 µM, respectively)
Formal name: N,N’-[1,4-phenylenebis[(1-methylethylidene)-4,1-phenylene]]bis[1,1,1-trifluoro-methanesulfonamide
Synonyms: Protein Tyrosine Phosphatase Inhibitor IV
Molecular weight: 608.6
CAS: 329317-98-8
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Inhibitors|Phosphatases||Research Area|Cell Biology|Cell Signaling